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Enzyme CoQ10

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The Carlton Clinic
Richard Snouffer, MD
1713 Hamric Dr. East, Suite B
Oxford, Alabama  36203

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Enzyme CoQ10

Coenzyme Q10, or CoQ10, is a vital nutrient for the production of energy.  It is so important that it is found in every cell of the body, which lead its discoverers to name it “ubiquinone” from the word “ubiquitous” meaning “everywhere.” 


In addition to the production of energy in the body, CoQ10 is a powerful antioxidant.  Specifically, CoQ10 is known to prevent the oxidation of LDL cholesterol in the body.  When LDL is oxidized, it becomes much more likely to stick to the walls of the arteries causing the plaques that block them, known as atherosclerosis.  These plaques can later rupture, causing clotting within the artery and heart attack.  By preventing this oxidation, CoQ10 can lower the amount of artery-blocking atherosclerosis and ultimately may lower the risk of heart attacks. 


CoQ10 is also vital for production of energy in the mitochondria, which are the energy producing organelle of the cells in your body.  CoQ10 is a critical component in the electron transport chain and acts as both an electron and a proton carrier during energy production.  What this means is that essentially, energy is not able to be properly produced without CoQ10, and if the body is low on CoQ10, energy production is much more inefficient.  This means trouble, especially for your body’s cells that have a high-energy metabolism, like muscles, especially the heart muscle. 


In clinical trials, supplementation with CoQ10 has been shown to:

  • Prevent physical fatigue,
  • Increase energy
  • Preserve levels of vitamin C and E in the body,
  • Lower markers of muscle damage after strenuous exercise,
  • Lower blood pressure,
  • Help prevent damage and improved heart function,
  • Lower cardiac risk in those with metabolic syndrome,
  • Lower levels of known markers of oxidative stress,
  • Lower inflammation
  • Improve outcomes in patients undergoing cardiac surgery,
  • Decrease re-oxygenation stress following episodes of the heart muscle not getting enough oxygen
  • Slow the progress of Alzheimer’s by reducing beta-amyloid protein (the main component of senile plaques in the brain) production and deposition  (up to a 44% reduction in disease progression compared to a placebo group after eight months of treatment)


Dosing of CoQ10:

Effective and safe doses have ranged in clinical studies from 50mg up to 1200 mg daily. 

  • The upper part of this range has mainly been in studies on the treatment of Alzheimer’s patients. 
  • Cardiac doses usually run between 50mg and 200mg daily.
  • Fibromyalgia patients often show improvement with 200-500mg daily.
  • Patients taking a medicine that lower CoQ10 levels, such as glucophage, Statin medications for cholesterol or Beta Blockers usually need extra CoQ10.  These patients should consult an Integrative/Anti Aging physician prior to taking CoQ10. 


Precautions with CoQ10:

  • No maximum safe dosage has been found.  This is because every dose studied so far has been found to be safe.  However, this does NOT mean that one should try dosages greater than those recommended by their physician.  Patients are urged to follow the directions of their Integrative/Anti Aging physician regarding administration of CoQ10.
  • Since CoQ10 can lower blood pressure, patients taking blood pressure medications should use extra caution when taking CoQ10.
  • CoQ10 can interact with medications.  Patients taking any medications should discuss CoQ10 with their Integrative/Anti Aging physician.
  • There have been some reports that some supplements of Enzyme CoQ10 can elevate liver enzymes.  Therefore, people with liver disease, or those taking medications that may harm the liver should consult their Integrative/Anti Aging physician prior to starting supplementation with CoQ10. 
  • Pregnant and breastfeeding women should consult their Pediatrician before taking CoQ10. 


The Carlton Clinic offers high-quality CoQ10 supplements.  Patients of Dr. Snouffer or The Carlton Clinic may sign up on the right-hand side of this page to purchase CoQ10 directly from MD Prescriptives.  You will need Dr. Snouffer's name and office phone number to sign up.

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Copyright © Richard Snouffer, MD
The Carlton Clinic
1713 Hamric Drive East, Suite B
Oxford, Alabama  36203